| BC Generations Project | HMC000045 | population-based cohort; prevention; chronic disease risk | 29852 | cancer, chronic disease | British Columbian adults | Buffy Coat, DNA, Dried Blood Spots, Red Blood Cells, Serum, Urine, Whole Blood | Genomics, Metabolomics | Genomic Profiling by Array (Affymetrix 2.0 UK Biobank gene chip), SNP Array | Canadian Partnership Against Cancer, BC Cancer Foundation, BC Cancer Agency |
| Integration of Environmental and Genomic Risk Factors to Predict Fibrotic Interstitial Lung Disease (fILD) Progression | HMC000049 | Genomics, Epigenomics, Air pollution | 1000 | interstitial lung disease | Canadian Registry for Pulmonary Fibrosis (CER-PF) | Air, DNA | Epigenomics, Exposomics, Genomics | DNA Methylation: Infinium Methylation EPIC array, Environment, Whole Genome Shotgun sequencing, methylation Quantitative Trait Loci (meQTLs) | Genome British Columbia |
| Epigenetic Profiling of Human Chondrosarcoma | HMC000062 | chondrosarcoma, RNA-seq, Marathon of Hope, genomics | 42 | bone cancer, chondrosarcoma, cancer | Tumour, Normal | Chondrosarcoma, DNA | Genomics, Transcriptomics | RNA-seq, Whole Genome Sequencing (WGS) | Marathon of Hope Cancer Centres Networks |
| BQC19: Biobanque québécoise de la COVID-19 | HMC000096 | COVID-19, biobank, multiomics, longitudinal study | 6272 | COVID-19, severe COVID-19, non-severe COVID-19, long COVID, critical COVID-19 | SARS-CoV-2 Positive patients, Mother and Child Centre, SARS-CoV-2 Negative patients | DNA, PBMC, Plasma, RNA, SARS-CoV-2 viral DNA, Serum | Genomics, Metabolomics, Proteomics, Transcriptomics | Genome-Wide Association Study (GWAS), Metabolon, Neutralizing antibodies against SARS-CoV-2, OLINK, RNA-seq, Roche Diagnostics, SARS-CoV-2 specific antibodies detected by ELISA, SomaLogic, Whole Genome Sequencing (WGS) | FRQS (Fonds de Recherche du Quebec-Sante), Quebec's Ministry of Health and Social Services, Public Health Agency of Canada, Genome Quebec |
| Mining The Infant Gut Microbiota To Predict And Prevent Asthma: Data From The CHILD Cohort Study | HMC000097 | | 3621 | childhood-onset asthma | Definite Asthma, No Asthma, Possible Asthma | Breast Milk, Cord Blood, Cord blood mononuclear cells (CBMC), DNA, Dust, PBMC, Plasma, RNA, Saliva/Buccal swabs, Serum, Stool, Swab (nasal), Urine, Whole Blood | Epigenomics, Genomics, Hormones, Lipidomics, Metabolomics, Microbiomics, Proteomics | Amplicon Sequencing (16S), Amplicon Sequencing (ITS), DNA Methylation: Infinium Methylation EPIC array, Gas liquid chromatography, Genotyping data using the HumanCoreExome BeadChip (Illumina), High performance liquid chromatography, Kits precoated with the antibody to each hormone purchased from Mesoscale Discovery, OLINK, Shotgun Metagenomic DNA Sequencing, Specific gravity corrected concentrations (nanograms/ml) of phthalate ester metabolites, Targeted liquid chromatography with tandem mass spectrometry (LC-MS/MS) assays, Targeted nuclear magnetic resonance (NMR) | Genome British Columbia, AllerGen Networks of Centres of Excellence, Canadian Institutes of Health Research (CIHR), Genome Canada |
| International Clinical Outcome Study for Dysferlinopathy (Jain COS 1) | HMC000089 | limb-girdle muscular dystrophy 2B, LGMD2b, limb girdle muscular dystrophy type R2, LGMDR2, Miyoshi Myopathy type 1, MMD1, dysferlinopathy | 187 | autosomal recessive limb-girdle muscular dystrophy type 2B, Miyoshi Myopathy type 1 (MM1), Autosomal recessive limb-girdle muscular dystrophy type R2 dysferlin related (LGMDR2) , dysferlinopathy | dysferlinopathy | DNA, Plasma, RNA, Serum, Skin fibroblasts | | | Jain Foundation |