| BC Generations Project | HMC000045 | population-based cohort; prevention; chronic disease risk | 29852 | cancer, chronic disease | British Columbian adults | Buffy Coat, DNA, Dried Blood Spots, Red Blood Cells, Serum, Urine, Whole Blood | Genomics, Metabolomics | Genomic Profiling by Array (Affymetrix 2.0 UK Biobank gene chip), SNP Array | Canadian Partnership Against Cancer, BC Cancer Foundation, BC Cancer Agency |
| Better Biomarkers For Transplantation | HMC000048 | cardiac transplant, renal transplant, liver transplant, acute rejection, chronic rejection, diagnostic, prognostic, biomarkers | 767 | heart transplant, kidney transplant, liver transplant, end-stage organ failure | Solid organ transplant recipients | Buffy Coat, Heart biopsy, Kidney biopsy, Liver biopsy, Plasma, Serum, Urine, Whole Blood | Metabolomics, Proteomics, Transcriptomics | Expression Profiling by Array (Affymetrix HG U133 plus 2), Expression profiling by array (Affymetrix HU Gene 1.1 ST), Isobaric tag for relative and absolute quantitation (iTRAQ), Multiple Reaction Monitoring (MRM) with Mass Spectrometry (MS), Nuclear Magnetic Resonance spectroscopy (NMR) | Genome British Columbia, St. Paul's Hospital Foundation, Astellas, IBM, Novartis Pharma, Genome Canada |
| BQC19: Biobanque québécoise de la COVID-19 | HMC000096 | COVID-19, biobank, multiomics, longitudinal study | 6272 | COVID-19, severe COVID-19, non-severe COVID-19, long COVID, critical COVID-19 | SARS-CoV-2 Positive patients, Mother and Child Centre, SARS-CoV-2 Negative patients | DNA, PBMC, Plasma, RNA, SARS-CoV-2 viral DNA, Serum | Genomics, Metabolomics, Proteomics, Transcriptomics | Genome-Wide Association Study (GWAS), Metabolon, Neutralizing antibodies against SARS-CoV-2, OLINK, RNA-seq, Roche Diagnostics, SARS-CoV-2 specific antibodies detected by ELISA, SomaLogic, Whole Genome Sequencing (WGS) | FRQS (Fonds de Recherche du Quebec-Sante), Quebec's Ministry of Health and Social Services, Public Health Agency of Canada, Genome Quebec |
| Mining The Infant Gut Microbiota To Predict And Prevent Asthma: Data From The CHILD Cohort Study | HMC000097 | | 3621 | childhood-onset asthma | Definite Asthma, No Asthma, Possible Asthma | Breast Milk, Cord Blood, Cord blood mononuclear cells (CBMC), DNA, Dust, PBMC, Plasma, RNA, Saliva/Buccal swabs, Serum, Stool, Swab (nasal), Urine, Whole Blood | Epigenomics, Genomics, Hormones, Lipidomics, Metabolomics, Microbiomics, Proteomics | Amplicon Sequencing (16S), Amplicon Sequencing (ITS), DNA Methylation: Infinium Methylation EPIC array, Gas liquid chromatography, Genotyping data using the HumanCoreExome BeadChip (Illumina), High performance liquid chromatography, Kits precoated with the antibody to each hormone purchased from Mesoscale Discovery, OLINK, Shotgun Metagenomic DNA Sequencing, Specific gravity corrected concentrations (nanograms/ml) of phthalate ester metabolites, Targeted liquid chromatography with tandem mass spectrometry (LC-MS/MS) assays, Targeted nuclear magnetic resonance (NMR) | Genome British Columbia, AllerGen Networks of Centres of Excellence, Canadian Institutes of Health Research (CIHR), Genome Canada |