Data Entry Maintenance

Metadata Commons Identifier

HMC000061

Project Title

Targeting SS18::SSX Biology In Synovial Sarcomagenesis

Project Description

Genomic, transcriptomic and epigenomic profiling of primary and untreated synovial sarcoma tumours.  Dataset includes ChIP-seq, RNA-seq, whole genome sequencing, whole genome bisulfite sequencing, scATAC-seq, bimodal methylation data. Samples were collected during surgery and flash frozen for omics. Samples have been collected from different body sites depending on primary tumour location. See publication link methods for more detailed information on samples collection and data generation.  dbGAP accession number includes published data for ChIPseq, WGBS, RNA-seq.  Accession: phs003646 (not yet published).  All other data is unpublished and may be available via contacting project contact email.  Other related metadata: HMC000077 'Simultaneous Genetic and Epigenetic Analysis with Biomodal Duet Multiomics Solution +modC'

Project Funder(s)

Canadian Institutes of Health Research (CIHR), Marathon of Hope Cancer Centres Networks, Terry Fox Research Institute

Project Institution(s)

University of British Columbia, Univeristy of Utah, Memorial Sloan Kettering Cancer Centre

Project Investigator(s)

Martin Hirst, Torsten Nielsen, Kevin Jones, Michael Underhill

Data Access Request URL*

Keywords

Synovial Sarcoma, Epigenetics, cancer, fusion oncoprotein

Publication Link

https://pubmed.ncbi.nlm.nih.gov/38798672/

Study Completed

Cohort Name

Synovial Sarcoma

Cohort Size

Disease/Condition Studied

synovial sarcoma, cancer

Enrollment Time Window

Biobanking Consent Available

Medical History Available

Ethnicity Availability

Time Course

Patient Phenotypes

Synovial Sarcoma Diagnosis

Patient Outcomes

Clinical Data Types Available

Age, Sex, Histology, Fusion Type, Location of tumour, Metastatic Event, Status

Time Course Data Points

Enrollment City

Groups

Project

Cohort

Enrollment City

Groups

Samples and Omics