Data Entry Maintenance

Metadata Commons Identifier

HMC000054

Project Title

DNA Methylation Analysis Of A Subset Of Children From The Canadian Asthma Primary Prevention Study

Project Description

<p style="mso-margin-top-alt: auto; mso-margin-bottom-alt: auto;" class="MsoNormal">The Canadian Asthma Primary Prevention Study (CAPPS) is a prospective longitudinal birth cohort developed to study the impact of a multi-faceted early life intervention on the development of asthma in children at high risk. DNA methylation (DNAm) analysis was performed on some participants with the aim of identifying new CpG sites where DNAm is associated with asthma or allergic disease. Illumina Methyl capture EPIC data was generated from cord blood or whole blood in children on at least one of the following three time points: at birth, year 7 and year 15. Methyl capture data was generated for 114 mothers as well. DNA methylation data at two time points are available for 99 children; and for 89 children at three time points.</p>

Project Funder(s)

Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC)

Project Institution(s)

Centre for Heart Lung Innovation

Project Investigator(s)

Denise Daley

Data Access Request URL*

Keywords

Asthma, DNA methylation

Publication Link

Study Completed

Cohort Name

Canadian Asthma Primary Prevention Study (CAPPS)

Cohort Size

632

Disease/Condition Studied

asthma, allergic disease

Enrollment Time Window

Biobanking Consent Available

Medical History Available

Ethnicity Availability

Time Course

Patient Phenotypes

asthma

Patient Outcomes

Clinical Data Types Available

Time Course Data Points

Birth, Year 7 and Year 15

Enrollment City

Groups

Project

Cohort

Enrollment City

Groups

Samples and Omics